HYALO4 CARE CREAM PLUS
A SYNERGIC FORMULATION FOR
PROMOTION OF HEALING AND
PREVENTION OF INFECTION3
PROMOTION OF HEALING AND
PREVENTION OF INFECTION3
composition
Hyaluronic Acid Sodium Salt 0.2% –
Silver Sulfadiazine 1%
Packaging Details
Cream Plus | 100 g for topical use
Classification
Class III – Medical Device – CE 0459
INDICATIONS
HYALO4 Cream Plus is indicated for the management of skin lesions, especially those at high risk of infection. In particular it is intended to cover acute and chronic wounds and to provide a moist microbe-free wound environment.
HYALO4 Cream Plus can be used on non-infected wounds to help prevent infection and, following successful treatment of infected wounds, to help prevent reoccurance of infection1.
PRESSURE SORES
VASCULAR ULCERS OF LEGS
FIRST AND SECOND-DEGREE BURNS
ADVANTAGES
- Silver Sulfadiazine (SSD) prevents microbial contamination, thus improving the Hyaluronic Acid ability to support wound healing1
- Effective against various species of fungi2
- HA + SSD showed significant statistic and clinical effectiveness in reducing wound size, protecting the surrounding skin, and preventing bacterial infection3
- Demonstrated faster wound healing time than SSD alone in second degree burns4
References:
1. HYALO4 CARE CREAM PLUS Indications for use
2. Farris A, et al. Association of hyaluronic acid and silver sulfadiazine for topical use: rational basis and recent clinical evidence in wound healing. Farmaci 2010;9:61-7
3.De Francesco F, Riccio M, Jimi S. Contribution of Topical Agents such as Hyaluronic Acid and Silver Sulfadiazine to Wound Healing and Management of Bacterial Biofilm Medicina 2022, 58, 835.
4.Costagliola M, Agrosì M. Second-degree burns: a comparative, multicenter, randomized trial of hyaluronic acid plus silver sulfadiazine vs. silver sulfadiazine alone. Curr Med Res Opin. 2005 Aug;21(8):1235-40
1. HYALO4 CARE CREAM PLUS Indications for use
2. Farris A, et al. Association of hyaluronic acid and silver sulfadiazine for topical use: rational basis and recent clinical evidence in wound healing. Farmaci 2010;9:61-7
3.De Francesco F, Riccio M, Jimi S. Contribution of Topical Agents such as Hyaluronic Acid and Silver Sulfadiazine to Wound Healing and Management of Bacterial Biofilm Medicina 2022, 58, 835.
4.Costagliola M, Agrosì M. Second-degree burns: a comparative, multicenter, randomized trial of hyaluronic acid plus silver sulfadiazine vs. silver sulfadiazine alone. Curr Med Res Opin. 2005 Aug;21(8):1235-40